Millions of Britons will fall silent at 11am today to show their respect to those affected by war.
Thousands of services will take place across Britain in offices, schools, town halls and at memorials, with many wearing a single poppy to show solidarity.
War veterans will pay their respects at the Cenotaph in London for a Remembrance Sunday service, led by the Prince of Wales.
It is the first time Charles has taken the symbolic role while the Queen is still in the UK.
The Queen and Duke of Edinburgh will observe the service from a balcony, while senior members of the royal family and political leaders lay wreaths.
The Cenotaph ceremony is a poignant and significant event in the life of the nation which normally involves the Queen leading the country in remembering those who have died in world wars and other conflicts.
Charles’ turn in leading the Whitehall service will therefore be a significant moment.
Buckingham Palace announced the change last month, which is seen as an example of the subtle shift of head of state duties from the Queen to the heir to the throne.
Earlier this year, Philip, 96, retired from his solo public duties, but on occasion has joined the Queen at her official engagements.
Philip’s equerry will lay his wreath, Buckingham Palace has said, while Charles will also lay his own wreath.
Charles has laid a wreath before on behalf of the Queen, in 1983 when she was out of the country, and when the Queen was in South Africa in 1999 she laid a wreath at the Cenotaph in Durban.
The Queen is expected to be joined by other royal women such as the Duchess of Cambridge, Duchess of Cornwall and the Countess of Wessex, in observing the service.